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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Lemont Kier ： ウィキペディア英語版 Lemont Kier Lemont Kier (born September 13, 1930) is an American chemist and researcher in the field of drug design and medicinal chemistry.〔See, for instance ''Richmond Times and Dispatch'', Feb. 26, 2004 "Three Named Top Virginia Scientists"〕 He is the recipient of the American Association of Pharmaceutical Scientists 2008 Research Achievement Award in Drug Development and Discovery.〔http://www.aapspharmaceutica.com/inside/awards_fellows/awardslist.asp〕 He obtained his PhD in Medicinal Chemistry at the University of Minnesota in 1958 and is currently a Professor of Medicinal Chemistry and Nurse Anesthesia at the Virginia Commonwealth University in Richmond, Virginia. Kier participated in the founding of the Center for the Study of Biological Complexity at Virginia Commonwealth University.〔L. B. Kier, My Journey Through Structure: The Structure of My Journey, Internet Electron. J. Mol. Des. 2006, 5, 181–191, ()〕 ==Work== Kier built one of the first models in which molecular orbital theory was applied successfully to drug design and development. In this model, he and his colleague developed what is now called the "Kier-Hall Index" to describe molecular connectivity.〔"From chemical topology to three-dimensional geometry" by Alexandru T. Balaban, Springer Books, 1997, p. 7〕〔Molecular drug properties: measurement and prediction - Google Books Result by Raimund Mannhold, Wilel VVH (2007) pp. 88-90〕 His particular expertise in the question “How do chemical modifications affect particular physical properties of drugs?” has been used to develop the theory of the interaction of general anesthetic gases with the body,〔''Molecular Connectivity and SAR of General Anesthetics.'' T. Dipaolo, L. B. Kier and L. H. Hall, Molec. Pharmacol., 13, 31 (1977)〕 and the theory of taste (and in particular, sweetness). Professor Kier is the author or co-author of eight books: ''Molecular Orbital Theory In Drug Research;'' 〔''Molecular Orbital Theory In Drug Research''. L. B. Kier, Academic Press, New York (1971)〕 ''Molecular Connectivity In Chemistry and Drug Research;'' 〔''Molecular Connectivity In Chemistry and Drug Research'' L. B. Kier and L. H. Hall, Academic Press, New York (1976)〕''Molecular Connectivity in Structure Activity Analysis;''〔''Molecular Connectivity in Structure Activity Analysis''. L. B. Kier and L. H. Hall, John Wiley Publ, London (1986)〕 ''Molecular Structure Description: The Electrotopological State;''〔''Molecular Structure Description: The Electrotopological State'' L. B. Kier and L. H. Hall, Academic Press, San Diego, (1999)〕 ''Medicinal Chemistry and Physics for Nurse Anesthetists; ''〔''Medicinal Chemistry and Physics for Nurse Anesthetists'' L. B. Kier and C. Dowd Amer. Assoc. of Nurse Anesthetists, Chicago (2004)〕 ''Cellular Automata Modeling of Chemical Systems;''〔''Cellular Automata Modeling of Chemical Systems''. L. B. Kier, P. G. Seybold and C.-K. Cheng, Springer, Amsterdam (2005)〕 and ''Science and Complexity for Life Science Students.''〔''Science and Complexity for Life Science Students''. L. B. Kier, Kendall/Hunt, Dubuque, IO, (2007)〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Lemont Kier」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.